Description

2-Chloro-6-(β-D-2-Deoxyribofuranosyl)-3,5-Diaminopyrazine is a specialized nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate for the creation of novel antiviral and anticancer agents, particularly in the development of modified nucleoside therapeutics. It is primarily needed by R&D chemists and process development scientists within the pharmaceutical, biotechnology, and fine chemical synthesis industries.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral drugs.
• Anticancer Drug Research: Used in the development of chemotherapeutic agents that target DNA replication and repair mechanisms.
• Biochemical Probe Synthesis: Serves as a precursor for labeled compounds used in metabolic pathway studies and enzyme inhibition assays.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	2-Chloro-6-(β-D-2-Deoxyribofuranosyl)-3,5-Diaminopyrazine
CAS No.	173256-61-6
Molecular Formula	C9H12ClN5O3
Molecular Weight	273.68 g/mol
Synonyms	2-Chloro-6-(2-deoxy-β-D-ribofuranosyl)-3,5-pyrazinediamine; 3,5-Diamino-2-chloro-6-(2-deoxy-β-D-erythro-pentofuranosyl)pyrazine; 2-Chloro-6-(2-deoxy-β-D-erythro-pentofuranosyl)-3,5-pyrazinediamine; 2-Chloro-6-(β-D-2'-deoxyribofuranosyl)-3,5-diaminopyrazine; Deoxyribofuranosyl diaminopyrazine derivative; Nucleoside analog intermediate; CAS 173256-61-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(β-D-2-Deoxyribofuranosyl)-3,5-Diaminopyrazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.