Description

(S)-5-Aminopiperidin-2-One is a high-purity chiral piperidinone derivative, serving as a critical building block in modern organic synthesis. Its value lies in its enantiomeric purity and functionalized ring structure, which are essential for constructing complex molecules with specific biological activity. This intermediate is primarily needed by pharmaceutical and biotechnology companies engaged in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potent, selective drug candidates, including protease inhibitors and receptor modulators.
• API Development: Used in constructing the core scaffold for potential treatments in neurological and psychiatric disorders.
• Asymmetric Synthesis: Employed as a starting material or intermediate in catalytic asymmetric reactions to introduce stereochemical complexity.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Peptidomimetics: Incorporated into the design of peptide-like compounds to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds to study enzyme function and biological pathways.

Basic Information

Product Name	(S)-5-Aminopiperidin-2-One
CAS No.	172913-97-2
Molecular Formula	C5H10N2O
Molecular Weight	114.15 g/mol
Synonyms	(S)-5-Amino-2-piperidinone; (S)-5-Amino-2-piperidone; (S)-5-Aminopiperidin-2-one; (S)-2-Oxo-5-aminopiperidine; (S)-5-Amino-δ-valerolactam; (S)-5-Aminopiperidinone; (S)-5-Azaniumylpiperidin-2-one; (S)-5-Aminopiperidin-2-One Hydrochloride (salt form)
EINECS	Contact for details

Quality Control

Our (S)-5-Aminopiperidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), enantiomeric excess (ee), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.