Description

(2S)-2-[[4-[(2,7-Dimethyl-4-Oxo-1H-Quinazolin-6-Yl)Methyl-Prop-2-Ynyl-Amino]-2-Fluoro-Benzoyl]Amino]-4-(2H-Tetrazol-5-Yl)Butanoic Acid CAS NO 172521-94-7 is a high-purity, non-peptidic small molecule compound featuring a complex quinazolinone-tetrazole pharmacophore. This molecule is of significant interest for its potential as a key intermediate or active pharmaceutical ingredient (API) in advanced drug discovery programs. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing novel therapeutics, particularly in areas requiring targeted molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates targeting specific enzymes or receptors.
• Biochemical Research: Used as a reference standard or probe compound in in vitro and in vivo studies to investigate biological pathways and mechanisms of action.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization due to its quinazolinone and tetrazole functional groups.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	(2S)-2-[[4-[(2,7-Dimethyl-4-Oxo-1H-Quinazolin-6-Yl)Methyl-Prop-2-Ynyl-Amino]-2-Fluoro-Benzoyl]Amino]-4-(2H-Tetrazol-5-Yl)Butanoic Acid
CAS No.	172521-94-7
Molecular Formula	C26H23FN8O4
Molecular Weight	530.52 g/mol
Synonyms	4-(2H-Tetrazol-5-yl)-2-[[4-[[(2,7-dimethyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynyl-amino]-2-fluorobenzoyl]amino]butanoic acid; (2S)-2-[[4-[(2,7-Dimethyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynyl-amino]-2-fluorobenzoyl]amino]-4-(1H-tetrazol-5-yl)butanoic acid; UNII-9J3V8V4D4F; 9J3V8V4D4F; L-742,694; L742694; (S)-2-((4-((((2,7-Dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)(prop-2-yn-1-yl)amino)-2-fluorobenzoyl)amino)-4-(1H-tetrazol-5-yl)butanoic acid
EINECS	Contact for details

Quality Control

Our (2S)-2-[[4-[(2,7-Dimethyl-4-Oxo-1H-Quinazolin-6-Yl)Methyl-Prop-2-Ynyl-Amino]-2-Fluoro-Benzoyl]Amino]-4-(2H-Tetrazol-5-Yl)Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.