Description

1-[(tert-Butyl)Oxycarbonyl]-3-Benzylpiperidine-3-Carboxylic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in peptide mimetics, drug discovery, and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Chemistry: Used to construct non-natural amino acid residues that enhance the stability and bioavailability of peptide-based therapeutics.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group provides orthogonal protection for the amine functionality in multi-step synthetic sequences.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: A valuable reagent for methodology development and the exploration of new synthetic routes in university laboratories.

Basic Information

Product Name	1-[(tert-Butyl)Oxycarbonyl]-3-Benzylpiperidine-3-Carboxylic Acid
CAS No.	170838-83-2
Molecular Formula	C18H25NO4
Molecular Weight	319.40 g/mol
Synonyms	3-Benzyl-1-[(tert-butoxy)carbonyl]piperidine-3-carboxylic acid; 1-Boc-3-benzylpiperidine-3-carboxylic acid; 1-N-Boc-3-benzyl-3-piperidinecarboxylic acid; 3-Benzyl-1-Boc-piperidine-3-carboxylic acid; 1-(tert-Butoxycarbonyl)-3-benzylpiperidine-3-carboxylic acid; 3-Benzyl-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid; 170838-83-2; tert-Butyl 3-benzyl-3-(carboxy)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-[(tert-Butyl)Oxycarbonyl]-3-Benzylpiperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.