Description

1-Boc-2-(2-Oxoethyl)Piperidine is a versatile and high-purity protected piperidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its primary value lies in enabling the efficient construction of complex nitrogen-containing heterocycles, which are core scaffolds in numerous bioactive molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of piperidine-based drug candidates targeting central nervous system (CNS) disorders, analgesics, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that incorporate functionalized piperidine motifs.
• Peptidomimetics & PROTACs: Serves as a crucial component in the design and synthesis of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) for drug discovery.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands or catalysts used in enantioselective synthesis.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and for exploring new chemical space in medicinal chemistry programs.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for clients.

Basic Information

Product Name	1-Boc-2-(2-Oxoethyl)Piperidine
CAS No.	170491-61-9
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	1-Boc-2-(2-Oxoethyl)piperidine; tert-Butyl 2-(2-oxoethyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-(2-oxoethyl)piperidine; 2-(2-Oxoethyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-2-(2-oxoethyl)piperidine; 1-Boc-2-(oxoethyl)piperidine; Piperidine, 1-[(1,1-dimethylethoxy)carbonyl]-2-(2-oxoethyl)-; 170491-61-9
EINECS	Contact for details

Quality Control

Our 1-Boc-2-(2-Oxoethyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.