Description

tert-Butyl-4-Benzyl-2(R)-Methyl-Piperazinecarboxylate is a high-purity, chiral piperazine derivative used as a critical intermediate in advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex molecules with specific stereochemistry. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Utilized in the construction of complex, stereochemically defined molecules for medicinal chemistry and catalyst development.
• Peptidomimetic Chemistry: Serves as a constrained scaffold in the design and synthesis of peptide analogs and protease inhibitors.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new synthetic pathways.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value compounds.

Basic Information

Product Name	tert-Butyl-4-Benzyl-2(R)-Methyl-Piperazinecarboxylate
CAS No.	170033-58-6
Molecular Formula	C17H26N2O2
Molecular Weight	290.40 g/mol
Synonyms	1-Boc-4-Benzyl-2(R)-Methylpiperazine; (R)-1-tert-Butyl 4-Benzyl 2-Methylpiperazine-1,4-dicarboxylate; (R)-1-(tert-Butoxycarbonyl)-4-benzyl-2-methylpiperazine; tert-Butyl (R)-4-benzyl-2-methylpiperazine-1-carboxylate; (R)-1-Boc-4-benzyl-2-methylpiperazine; Boc-4-Bn-2(R)-Me-piperazine; 170033-58-6
EINECS	Contact for details

Quality Control

Our tert-Butyl-4-Benzyl-2(R)-Methyl-Piperazinecarboxylate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.