Description

(R)-1-n-Boc-2-Methylpiperazine is a high-purity, chiral piperazine derivative, a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas like oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used to introduce the (R)-2-methylpiperazine moiety into target molecules, enabling the creation of enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new biological entities.
• Process Chemistry & Scale-Up: Employed in the development and optimization of commercial-scale manufacturing routes for pharmaceuticals.
• Protease Inhibitor Development: Potential application as a building block in the synthesis of inhibitors targeting specific enzymes.
• Ligand Synthesis: Can be utilized in the preparation of chiral ligands for catalytic asymmetric reactions.

Basic Information

Product Name	(R)-1-n-Boc-2-Methylpiperazine
CAS No.	170033-47-3
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	(R)-1-Boc-2-Methylpiperazine; (R)-2-Methyl-1-(tert-butoxycarbonyl)piperazine; tert-Butyl (R)-2-methylpiperazine-1-carboxylate; (R)-N-Boc-2-methylpiperazine; (R)-1-(tert-Butoxycarbonyl)-2-methylpiperazine; (R)-2-Methyl-1-Boc-piperazine; (R)-1-N-Boc-2-methylpiperazine; (R)-Boc-2-methylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-1-n-Boc-2-Methylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for advanced research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.