Description

Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor, a non-steroidal anti-inflammatory drug (NSAID) class compound. Its primary value lies in its targeted mechanism of action, which offers effective anti-inflammatory and analgesic properties while potentially reducing gastrointestinal side effects associated with traditional NSAIDs. This high-purity active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry, specifically for the formulation of prescription medications used to manage conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. Celecoxib CAS NO 169590-42-5 is a critical component in the production of modern therapeutic solutions.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription drug formulations for pain and inflammation management.
• Osteoarthritis Treatment: Formulation into medications designed to alleviate pain and improve joint function in patients with osteoarthritis.
• Rheumatoid Arthritis Management: Key component in drugs used to reduce inflammation and pain associated with rheumatoid arthritis.
• Acute Pain Relief: Used in the development of medications for the short-term treatment of acute pain.
• Research & Development: Serves as a reference standard and building block in pharmacological research for novel COX-2 inhibitors and anti-inflammatory agents.
• Generic Drug Manufacturing: Critical for companies producing bioequivalent generic versions of branded celecoxib medications.

Basic Information

Product Name	Celecoxib
CAS No.	169590-42-5
Molecular Formula	C17H14F3N3O2S
Molecular Weight	381.37 g/mol
Synonyms	4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; SC-58635; Celebrex (Trade Name); Celebra; Onsenal; Cox-2 Inhibitor; COX2 Inhibitor; YM 177
EINECS	Contact for details

Quality Control

Our Celecoxib is manufactured under strict quality management systems to ensure it meets the highest standards for pharmaceutical use. The product undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to confirm compliance with relevant pharmacopeial specifications such as USP and EP. A Certificate of Analysis (COA) is provided with each batch, detailing all test results and confirming its suitability as an Active Pharmaceutical Ingredient (API).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.