Description

1,2-Dipalmitoyl-Sn-Glycero-3-Phosphate is a high-purity, synthetic phospholipid, specifically a phosphatidic acid derivative, essential for advanced research and formulation development. This compound serves as a critical building block for constructing complex lipid membranes and vesicles, enabling precise control over biophysical properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors for applications such as liposome preparation, drug delivery systems, and membrane biophysics studies.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key phospholipid component for creating stable, uniform liposomes and LNPs used in drug and gene delivery systems.
• Membrane Biophysics Research: Used as a model lipid to study membrane structure, fluidity, and protein-lipid interactions in artificial bilayer systems.
• Biomimetic Coatings & Materials: Incorporated into surface coatings and materials to create biocompatible, cell-membrane-like interfaces.
• Pharmaceutical Excipient: Acts as a functional excipient in advanced parenteral formulations to enhance stability and bioavailability of active ingredients.
• Bioconjugation & Probe Synthesis: Serves as a starting material for synthesizing fluorescently labeled or functionalized phospholipid probes for diagnostic assays.
• Cosmetic Actives Carrier: Employed in high-end cosmetic formulations to encapsulate and deliver active ingredients to the skin.

Basic Information

Product Name	1,2-Dipalmitoyl-Sn-Glycero-3-Phosphate
CAS No.	169051-60-9
Molecular Formula	C35H69O8P
Molecular Weight	648.89 g/mol
Synonyms	DPPA; 1,2-Dipalmitoylphosphatidic acid; 1,2-Dihexadecanoyl-sn-glycero-3-phosphate; PA(16:0/16:0); Phosphatidic acid(16:0/16:0); 1,2-Dipalmitoyl-sn-glycerol-3-phosphate; sn-Glycero-3-phosphoric acid 1,2-dipalmitoyl ester; (2R)-2,3-Bis(hexadecanoyloxy)propyl dihydrogen phosphate
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and GMP-grade applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.