Description

4-(1-Piperidyl)-2-Propyl-3-[[4-[2-(2H-Tetrazol-5-Yl)Phenyl]Phenyl]Meth Yl]-1,5,7,9-Tetrazabicyclo[4.3.0]Nona-2,4,6,8-Tetraene is a sophisticated heterocyclic compound featuring a unique tetrazabicyclic core integrated with tetrazole and piperidine pharmacophores. This complex molecular architecture makes it a high-value intermediate for advanced research and development in medicinal chemistry. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of new drug candidates, particularly those targeting cardiovascular and central nervous system disorders.
• Angiotensin II Receptor Antagonist Research: The tetrazole moiety is a key structural feature in sartan-class drugs, making this compound valuable for developing next-generation antihypertensive agents.
• Medicinal Chemistry & Lead Optimization: Used by research chemists to explore structure-activity relationships (SAR) and to introduce specific pharmacophoric elements into novel molecular scaffolds.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and receptor binding studies due to its specific heterocyclic structure.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes for producing complex, high-value specialty chemicals for advanced applications.

Basic Information

Product Name	4-(1-Piperidyl)-2-Propyl-3-[[4-[2-(2H-Tetrazol-5-Yl)Phenyl]Phenyl]Meth Yl]-1,5,7,9-Tetrazabicyclo[4.3.0]Nona-2,4,6,8-Tetraene
CAS No.	168152-94-1
Molecular Formula	C28H30N10
Molecular Weight	506.61 g/mol
Synonyms	4-(1-Piperidyl)-2-propyl-3-({4'-[2-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl})-1,5,7,9-tetrazabicyclo[4.3.0]nona-2,4,6,8-tetraene; BIBR 277 diethyl ester analog; Tetrazabicyclononatetraene derivative; 1,5,7,9-Tetrazabicyclo[4.3.0]nona-2,4,6,8-tetraene, 4-(1-piperidinyl)-2-propyl-3-[[4'-[2-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-; Related to BIBR 277 series.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support development and cGMP-grade production to meet the exacting standards of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.