Description

Methyl 3-Nitro-4-(Piperazin-1-Yl)Benzoate is a high-purity, synthetically valuable organic compound featuring a benzoate ester core substituted with a nitro group and a piperazine moiety. This specific molecular architecture makes it a crucial pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with targeted biological activity.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a critical precursor in the development and scale-up of active pharmaceutical ingredients (APIs), particularly those requiring a functionalized piperazine-benzene scaffold.
• Building Block for Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, especially in therapeutic areas targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Intermediate: Employed in the synthesis of novel herbicides, fungicides, or insecticides where the nitro and piperazine groups contribute to biological efficacy.
• Fine Chemical Production: Acts as a specialized reagent for introducing specific functional groups into complex molecules in custom synthesis and contract manufacturing.
• Chemical Research & Development: Utilized in academic and industrial labs for methodological studies, such as novel coupling reactions or heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	Methyl 3-Nitro-4-(Piperazin-1-Yl)Benzoate
CAS No.	168123-39-5
Molecular Formula	C12H15N3O4
Molecular Weight	265.27 g/mol
Synonyms	Methyl 3-nitro-4-(piperazin-1-yl)benzoate; 3-Nitro-4-piperazin-1-yl-benzoic acid methyl ester; Methyl 4-(1-piperazinyl)-3-nitrobenzoate; Benzoic acid, 3-nitro-4-(1-piperazinyl)-, methyl ester; 168123-39-5; 4-Piperazin-1-yl-3-nitro-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Nitro-4-(Piperazin-1-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets exacting standards for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.