Description

1-Benzyl-3-(Trifluoromethyl)Piperazine is a high-value, functionalized piperazine derivative characterized by its benzyl and trifluoromethyl substituents. This compound is a crucial pharmaceutical intermediate and building block in advanced organic synthesis, prized for its ability to modulate the physicochemical and metabolic properties of target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Incorporated into polymers and advanced materials to impart specific fluorinated characteristics.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated nitrogen heterocycles.

Basic Information

Product Name	1-Benzyl-3-(Trifluoromethyl)Piperazine
CAS No.	167566-34-9
Molecular Formula	C12H15F3N2
Molecular Weight	244.26 g/mol
Synonyms	3-(Trifluoromethyl)-1-benzylpiperazine; 1-Benzyl-3-(trifluoromethyl)piperazine; N-Benzyl-3-(trifluoromethyl)piperazine; 3-Trifluoromethyl-1-benzylpiperazine; 1-Benzyl-3-trifluoromethylpiperazine; Benzyl(trifluoromethyl)piperazine; (Trifluoromethyl)benzylpiperazine
EINECS	Contact for details

Quality Control

Our 1-Benzyl-3-(Trifluoromethyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.