Description

Pyrrolo[1,2-A]Pyrazin-4(1H)-One, Hexahydro-3-Methyl-1-Thioxo-, (3S-Trans)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound with a thioxo functional group, serving as a critical advanced intermediate in modern synthetic chemistry. Its precise stereochemistry and unique fused ring system make it a valuable building block for constructing complex molecular architectures with specific biological activities. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used as a precursor in the design and synthesis of novel pesticides and herbicides, leveraging its heterocyclic core.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex nitrogen- and sulfur-containing heterocycles via various cyclization and functionalization reactions.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazin-4(1H)-One, Hexahydro-3-Methyl-1-Thioxo-, (3S-Trans)- (9Ci)
CAS No.	167391-76-6
Molecular Formula	C8H12N2OS
Molecular Weight	184.26 g/mol
Synonyms	(3S-trans)-Hexahydro-3-methyl-1-thioxopyrrolo[1,2-a]pyrazin-4(1H)-one; (3S,8aS)-3-Methyl-1-thioxooctahydropyrrolo[1,2-a]pyrazin-4-one; Hexahydro-3-methyl-1-thioxopyrrolo[1,2-a]pyrazin-4(1H)-one, (3S-trans)-; Pyrrolo[1,2-a]pyrazin-4(1H)-one, hexahydro-3-methyl-1-thioxo-, (3S-trans)-; CAS 167391-76-6
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-A]Pyrazin-4(1H)-One, Hexahydro-3-Methyl-1-Thioxo-, (3S-Trans)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.