Description

Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-4-Thioxo-, (S)- (9Ci) is a high-purity, chiral heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex, stereochemically defined active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for creating novel bioactive compounds.
• Asymmetric Synthesis: Serves as a starting material or intermediate in stereoselective synthesis routes due to its defined (S)-configuration.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and protein interactions.
• Academic Research: A valuable compound for university and institutional research in organic methodology development and heterocyclic chemistry.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-4-Thioxo-, (S)- (9Ci)
CAS No.	167391-75-5
Molecular Formula	C7H10N2OS
Molecular Weight	170.23 g/mol
Synonyms	(S)-Hexahydro-4-thioxopyrrolo[1,2-a]pyrazin-1(2H)-one; (S)-4-Thioxohexahydropyrrolo[1,2-a]pyrazin-1(2H)-one; (S)-4-Thioxo-1,2,3,4,6,7-hexahydropyrrolo[1,2-a]pyrazin-1-one; 167391-75-5; Pyrrolo[1,2-a]pyrazin-1(2H)-one, hexahydro-4-thioxo-, (S)-; (S)-enantiomer of Hexahydro-4-thioxopyrrolo[1,2-a]pyrazin-1(2H)-one
EINECS	Contact for details

Quality Control

Our Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-4-Thioxo-, (S)- (9Ci) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.