Description

tert-Butyl 4-Cyano-4-(Pyridin-2-Yl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its unique molecular architecture, which combines a cyano group and a pyridine moiety on a piperidine scaffold, making it a versatile building block for constructing complex bioactive molecules. This compound is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors for the discovery and production of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery programs.
• Kinase Inhibitor Development: Used in the research and production of small molecule kinase inhibitors, a major class of targeted cancer therapies.
• CNS Drug Research: Serves as a precursor in the synthesis of compounds targeting neurological disorders and psychiatric conditions.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Utilized in process research and development (PR&D) for optimizing synthetic routes from laboratory to commercial scale.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific novel chemical entities.

Basic Information

Product Name	tert-Butyl 4-Cyano-4-(Pyridin-2-Yl)Piperidine-1-Carboxylate
CAS No.	167263-04-9
Molecular Formula	C16H21N3O2
Molecular Weight	287.36 g/mol
Synonyms	1-Boc-4-cyano-4-(2-pyridyl)piperidine; tert-Butyl 4-cyano-4-(2-pyridinyl)-1-piperidinecarboxylate; 4-Cyano-4-(pyridin-2-yl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-cyano-4-(2-pyridyl)piperidine; Boc-4-cyano-4-(2-pyridyl)piperidine; 4-(2-Pyridyl)-4-cyanopiperidine-1-carboxylic acid tert-butyl ester; 167263-04-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Cyano-4-(Pyridin-2-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.