Description

Boc-4-(Naphthalen-2-Yl)-Piperidine-4-Carboxylic Acid CAS NO 167262-89-7 is a high-purity, protected amino acid derivative featuring a piperidine scaffold with a naphthyl substituent. This compound is a critical advanced pharmaceutical intermediate (API) used in the synthesis of complex bioactive molecules. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for developing new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Peptidomimetic Research: Used to incorporate constrained, lipophilic amino acid analogs into peptide chains to enhance metabolic stability and membrane permeability.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening campaigns.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical pathway analysis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	Boc-4-(Naphthalen-2-Yl)-Piperidine-4-Carboxylic Acid
CAS No.	167262-89-7
Molecular Formula	C22H25NO4
Molecular Weight	367.44 g/mol
Synonyms	1-Boc-4-(2-Naphthyl)-4-piperidinecarboxylic Acid; 4-(Naphthalen-2-yl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylic Acid; tert-Butyl 4-(naphthalen-2-yl)-4-(carboxy)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(2-naphthyl)piperidine-4-carboxylic Acid; Boc-4-(2-Naphthyl)-4-piperidinecarboxylic Acid; 1-Boc-4-(2-Naphthalenyl)-4-piperidinecarboxylic Acid; 4-(2-Naphthyl)-1-Boc-piperidine-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of Boc-4-(Naphthalen-2-Yl)-Piperidine-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.