Description

1-[4-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Phenyl]-Ethanone is a high-purity, functionalized piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both a ketone group and a hydroxylated piperazine moiety, which enables its use in creating complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its piperazine pharmacophore.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating chelating ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the development of specialty polymers with specific functional properties.
• Chemical Research: Utilized in academic and industrial R&D for exploring new reaction pathways and constructing heterocyclic compounds.
• Dye and Pigment Intermediate: Acts as a building block in the synthesis of complex organic dyes and functional colorants.

Basic Information

Product Name	1-[4-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Phenyl]-Ethanone
CAS No.	166438-77-3
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-[4-[4-(2-Hydroxyethyl)-1-piperazinyl]phenyl]ethanone; 4'-Acetyl-1-(2-hydroxyethyl)piperazine; 1-(4-(4-(2-Hydroxyethyl)piperazin-1-yl)phenyl)ethan-1-one; N-(2-Hydroxyethyl)-4-acetylpiperazine; 4-Acetylphenyl-1-(2-hydroxyethyl)piperazine; 1-(4-(4-(2-Hydroxyethyl)-1-piperazinyl)phenyl)ethanone; 2-[4-(4-Acetylphenyl)piperazin-1-yl]ethanol
EINECS	Contact for details

Quality Control

Our 1-[4-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Phenyl]-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and synthesis applications. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.