Description

1-(4-Methanesulfonyl-Phenyl)-Piperidin-4-Ol is a high-purity, synthetic organic compound featuring a piperidine core substituted with a methanesulfonylphenyl group, serving as a critical building block in advanced pharmaceutical research and development. This compound is valued for its role as a versatile synthetic intermediate, enabling the construction of complex molecules with potential biological activity. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new chemical entities (NCEs) targeting central nervous system (CNS) disorders, inflammation, or other therapeutic areas.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function or receptor interactions in biological systems.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control in regulatory submissions.
• Custom Synthesis Starting Material: Provides a functionalized core for contract research organizations (CROs) and CDMOs to perform bespoke synthesis for client projects.

Basic Information

Product Name	1-(4-Methanesulfonyl-Phenyl)-Piperidin-4-Ol
CAS No.	166438-65-9
Molecular Formula	C12H17NO3S
Molecular Weight	255.33 g/mol
Synonyms	4-Hydroxy-1-(4-(methylsulfonyl)phenyl)piperidine; 1-[4-(Methylsulfonyl)phenyl]-4-piperidinol; 4-Piperidinol, 1-[4-(methylsulfonyl)phenyl]-; 1-(4-Methanesulfonylphenyl)piperidin-4-ol; 1-(4-Methylsulfonylphenyl)piperidin-4-ol; 4-Hydroxy-1-(4-methanesulfonylphenyl)piperidine; 1-(4-(Methylsulfonyl)phenyl)piperidin-4-ol
EINECS	Contact for details

Quality Control

Our 1-(4-Methanesulfonyl-Phenyl)-Piperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.