Description

3-Methyl-7-Trifluoromethylquinoxaline-2(1H)-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, which combines a quinoxalinone core with a trifluoromethyl group, imparting desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by manufacturers of specialty chemicals and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Organic Light-Emitting Diodes (OLEDs): Serves as a potential electron-transport or host material precursor due to its rigid, conjugated quinoxaline structure.
• Coordination Chemistry & Ligand Synthesis: The nitrogen-rich heterocycle can be utilized to create novel chelating ligands for catalysis or material science.
• Fluorinated Building Block: An essential starting material for introducing the 7-trifluoromethylquinoxalinone scaffold into more complex molecular architectures.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the exploration of new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3-Methyl-7-Trifluoromethylquinoxaline-2(1H)-One
CAS No.	166402-52-4
Molecular Formula	C10H7F3N2O
Molecular Weight	228.17 g/mol
Synonyms	3-Methyl-7-(trifluoromethyl)quinoxalin-2(1H)-one; 7-Trifluoromethyl-3-methyl-1,2-dihydroquinoxalin-2-one; 3-Methyl-7-trifluoromethyl-2(1H)-quinoxalinone; 2(1H)-Quinoxalinone, 3-methyl-7-(trifluoromethyl)-; 1,2-Dihydro-3-methyl-7-(trifluoromethyl)quinoxalin-2-one
EINECS	Contact for details

Quality Control

Our 3-Methyl-7-Trifluoromethylquinoxaline-2(1H)-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.