Description

4-(3-Chloro-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a versatile and high-value piperazine derivative, serving as a critical protected intermediate in advanced organic synthesis. Its primary commercial value lies in enabling the efficient construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-purity building blocks for API synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those containing piperazine pharmacophores, such as antipsychotics, antidepressants, and antimicrobial agents.
• Chemical Synthesis Reagent: Used as a protected amine precursor in multi-step organic synthesis, allowing for selective reactions at other functional groups.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and insecticides that utilize heterocyclic amine structures.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal complexation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and clinical trial materials.
• Academic & R&D: Used in university and institutional laboratories for methodological development and exploratory research in medicinal chemistry.

Basic Information

Product Name	4-(3-Chloro-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	165530-45-0
Molecular Formula	C12H23ClN2O2
Molecular Weight	262.78 g/mol
Synonyms	1-Boc-4-(3-chloropropyl)piperazine; tert-Butyl 4-(3-chloropropyl)piperazine-1-carboxylate; 4-(3-Chloropropyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-(3-chloropropyl)-1-piperazinecarboxylate; N-Boc-4-(3-chloropropyl)piperazine; Piperazine, 4-(3-chloropropyl)-, 1-(1,1-dimethylethyl) 1-carboxylate; 165530-45-0; Boc-4-(3-chloropropyl)piperazine
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.