Description

2-(4-Aminopiperazin-1-Yl)Acetic Acid is a versatile and high-value piperazine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a reactive acetic acid moiety and a primary amine on the piperazine ring, makes it an essential intermediate for constructing complex molecular architectures. This compound is particularly valuable for pharmaceutical research and development, where it is used to synthesize novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the construction of core structures for potential APIs targeting neurological, oncological, and infectious diseases.
• Ligand and Chelator Development: Serves as a precursor for creating specialized ligands in catalysis and metal-chelating agents for diagnostic or therapeutic applications.
• Bioconjugation and Linker Chemistry: The amine and carboxylic acid functional groups enable its use as a spacer or linker molecule in bioconjugation for antibody-drug conjugates (ADCs) or probe development.
• Fine Chemical and Specialty Chemical Production: Employed in the synthesis of high-value, low-volume specialty chemicals for research and industrial applications.
• Agrochemical Research: Acts as a building block in the discovery and synthesis of new agrochemicals, such as herbicides or fungicides.

Basic Information

Product Name	2-(4-Aminopiperazin-1-Yl)Acetic Acid
CAS No.	164785-11-9
Molecular Formula	C6H13N3O2
Molecular Weight	159.19 g/mol
Synonyms	1-Piperazineacetic acid, 4-amino-; 4-Amino-1-piperazineacetic acid; 2-(4-Amino-1-piperazinyl)acetic acid; 2-(4-Aminopiperazin-1-yl)ethanoic acid; 4-Aminopiperazine-1-acetic acid; (4-Aminopiperazin-1-yl)acetic acid; 1-Carboxymethyl-4-aminopiperazine; UNII-1F2K0V5Y4P
EINECS	Contact for details

Quality Control

Our 2-(4-Aminopiperazin-1-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports applications in cGMP and research environments where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.