Description

2,5-Piperazinedione,3,6-Diethyl-,(3S-Cis)-(9Ci) is a specialized chiral piperazinedione derivative, a key structural motif in medicinal chemistry and advanced organic synthesis. This compound matters as a high-value building block for the development of novel pharmaceutical agents, particularly those targeting neurological and oncological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating complex molecules with specific stereochemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-cancer therapeutics.
• Asymmetric Synthesis: Used as a starting material or reagent in asymmetric catalytic reactions to introduce stereocenters into complex organic molecules.
• Peptidomimetic Research: Acts as a constrained dipeptide analog (diketopiperazine) in the design and synthesis of peptidomimetics to modulate protein-protein interactions.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme mechanisms and biological pathways.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: A valuable compound for university and institutional research in organic methodology development and medicinal chemistry projects.

Basic Information

Product Name	2,5-Piperazinedione,3,6-Diethyl-,(3S-Cis)-(9Ci)
CAS No.	164453-64-9
Molecular Formula	C8H14N2O2
Molecular Weight	170.21 g/mol
Synonyms	(3S,6S)-3,6-Diethylpiperazine-2,5-dione; (3S-cis)-3,6-Diethyl-2,5-piperazinedione; (3S,6S)-3,6-Diethyl-2,5-diketopiperazine; cis-3,6-Diethyl-2,5-piperazinedione; 3,6-Diethyl-2,5-diketopiperazine (cis-); (S,S)-3,6-Diethylpiperazine-2,5-dione; Diketopiperazine derivative, Diethyl- (cis, S,S); 2,5-Diketopiperazine, 3,6-diethyl-, (3S,6S)-
EINECS	Contact for details

Quality Control

Our high-purity chiral intermediates are manufactured under strict quality management systems. Each batch of 2,5-Piperazinedione,3,6-Diethyl-,(3S-Cis)-(9Ci) undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.