Description

tert-Butyl 4-(Methylsulfonyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). Pharmaceutical researchers and fine chemical manufacturers need it for creating novel drug candidates, especially in therapeutic areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Protease Inhibitor Development: Used in the research and production of protease inhibitors, leveraging the reactive methylsulfonyl and protected amine functionalities.
• Kinase Inhibitor Scaffold: Serves as a core structural element in the design and synthesis of potent kinase inhibitors for cancer therapy.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for drug discovery.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and herbicides.
• Material Science: Used in the synthesis of specialty polymers and advanced materials requiring specific piperazine-based monomers.

Basic Information

Product Name	tert-Butyl 4-(Methylsulfonyl)Piperazine-1-Carboxylate
CAS No.	164331-38-8
Molecular Formula	C10H20N2O4S
Molecular Weight	264.34 g/mol
Synonyms	1-Boc-4-(Methylsulfonyl)piperazine; 4-(Methylsulfonyl)-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; tert-Butyl 4-(Methanesulfonyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(methylsulfonyl)piperazine; N-Boc-4-(Methylsulfonyl)piperazine; Boc-4-(Methylsulfonyl)piperazine; 4-Methanesulfonyl-piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Methylsulfonyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.