Description

(S)-3-Methyl Piperidine Carboxylate Hydrochloride is a high-purity chiral piperidine derivative, a crucial building block in modern pharmaceutical synthesis. Its enantiomeric purity is vital for developing active pharmaceutical ingredients (APIs) with targeted biological activity and reduced side effects. This intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for projects involving chiral amines and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• API Development: Serves as a core structural component in the development of Active Pharmaceutical Ingredients (APIs) requiring the (S)-3-methylpiperidine moiety.
• Agrochemical Research: Potential application in the synthesis of chiral agrochemicals, such as herbicides or fungicides, where specific stereochemistry influences activity.
• Ligand & Catalyst Preparation: Useful for constructing chiral ligands and organocatalysts used in homogeneous catalysis.
• Academic & R&D: A valuable reagent for medicinal chemistry and organic synthesis research in academic and industrial R&D laboratories.

Basic Information

Product Name	(S)-3-Methyl Piperidine Carboxylate Hydrochloride
CAS No.	164323-84-6
Molecular Formula	C8H15NO2 • HCl
Molecular Weight	193.67 g/mol (Free base: 157.21)
Synonyms	(S)-3-Methylpiperidine-1-carboxylic acid hydrochloride; (S)-1-Carboxy-3-methylpiperidine hydrochloride; Methyl 3-methylpiperidine-1-carboxylate hydrochloride (S-enantiomer); (S)-N-Carbomethoxy-3-methylpiperidine hydrochloride; (S)-3-Methyl-1-piperidinecarboxylic acid methyl ester hydrochloride; (S)-3-Methylpipecolic acid methyl ester hydrochloride; (S)-3-Methyl-1-(methoxycarbonyl)piperidinium chloride
EINECS	Contact for details

Quality Control

Our (S)-3-Methyl Piperidine Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity, enantiomeric excess, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.