Description

Mazokalim CAS NO 164178-54-5 is a high-purity potassium channel opener used as a key pharmaceutical intermediate and research chemical. This compound is critical for the development and synthesis of novel therapeutic agents targeting cardiovascular and smooth muscle conditions. It is essential for pharmaceutical R&D laboratories, fine chemical synthesis, and academic research institutions focused on ion channel modulation.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of active pharmaceutical ingredients (APIs) for cardiovascular research.
• Biochemical Research: Tool compound for studying ATP-sensitive potassium (KATP) channels in cellular and molecular biology.
• Vasodilator Studies: Used in preclinical research to investigate mechanisms of vasodilation and smooth muscle relaxation.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Synthesis: Building block for creating analogs and derivatives with modified biological activity.

Basic Information

Item	Details
Product Name	Mazokalim
CAS No.	164178-54-5
Molecular Formula	C12H15N3O3S
Molecular Weight	281.33 g/mol
Synonyms	Mazokalim; 6-Cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-3-ol; PNU-94772; PNU 94772; Benzopyran derivative PNU-94772; Potassium channel opener PNU-94772; 2H-1-Benzopyran-3-ol, 6-cyano-3,4-dihydro-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-
EINECS	Contact for details

Quality Control

Our Mazokalim is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.