Description

1,6,7,8-Indolizinetetrol, Octahydro-, 6-(Dihydrogen Phosphate), 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a high-purity, stereochemically defined indolizine derivative, a class of compounds known for their significant biological activity. This compound matters as a critical advanced intermediate in the synthesis of complex pharmaceuticals and fine chemicals, offering researchers and manufacturers a reliable building block with precise stereochemistry. It is primarily needed by R&D and production teams in the pharmaceutical, biotechnology, and agrochemical industries for developing new therapeutic agents and high-value specialty products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for alkaloid-based therapeutics.
• Biochemical Research: Used as a reference standard or probe in enzymatic studies and metabolic pathway investigations due to its phosphorylated polyol structure.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct indolizidine and related nitrogen-containing heterocycles.
• Agrochemical Development: Serves as a precursor in the synthesis of new-generation, biologically active crop protection agents.
• Academic Research: Utilized in universities and research institutes for studying stereoselective reactions and natural product synthesis.

Basic Information

Product Name	1,6,7,8-Indolizinetetrol, Octahydro-, 6-(Dihydrogen Phosphate), 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	163814-80-0
Molecular Formula	C8H17NO7P
Molecular Weight	270.20 g/mol
Synonyms	1S-(1α,6β,7α,8β,8aβ)-Octahydro-1,6,7,8-indolizinetetrol 6-(Dihydrogen Phosphate); (1S,6R,7S,8R,8aR)-Octahydroindolizine-1,6,7,8-tetrol 6-Phosphate; 6-Phosphoryl-1,6,7,8-tetrahydroxyoctahydroindolizine (1S-isomer); Swainsonine Phosphate Intermediate; Indolizidine Polyol Phosphate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.