Description

tert-Butyl 3-(3-Hydroxypropyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring a Boc-protected amine and a terminal hydroxyl group, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system (CNS).
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the piperidine scaffold.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and conformationally restricted mimetics.
• Ligand & Catalyst Development: Useful for creating chiral ligands and organocatalysts due to its modifiable functional groups.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 3-(3-Hydroxypropyl)Piperidine-1-Carboxylate
CAS No.	163210-22-8
Molecular Formula	C13H25NO3
Molecular Weight	243.34 g/mol
Synonyms	1-Boc-3-(3-hydroxypropyl)piperidine; 3-(3-Hydroxypropyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-(3-hydroxypropyl)-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-3-(3-hydroxypropyl)piperidine; N-Boc-3-(3-hydroxypropyl)piperidine; 1-N-Boc-3-(3-hydroxypropyl)piperidine; 3-(3-Hydroxypropyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 163210-22-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(3-Hydroxypropyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.