Description

1-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine is a highly purified, structured phospholipid where the sn-1 position is esterified with docosahexaenoic acid (DHA), a critical ω-3 fatty acid. This molecular architecture is essential for advanced research and formulation in lipidomics, membrane biophysics, and the development of targeted lipid-based delivery systems. It is a vital raw material for pharmaceutical R&D, nutraceutical innovators, and manufacturers of specialized liposomal products seeking to leverage the cognitive and anti-inflammatory benefits of DHA within a stable phospholipid carrier.

Application

• Pharmaceutical Research & Drug Delivery: A key component in the formulation of advanced liposomes and lipid nanoparticles (LNPs) for targeted drug delivery, particularly for neurological and anti-inflammatory therapeutics.
• Nutraceutical & Functional Food Development: Used to create high-bioavailability DHA supplements and fortified food products, enhancing the stability and cellular uptake of ω-3 fatty acids.
• Biomembrane & Lipidomics Studies: Serves as a standard and model lipid for investigating membrane fluidity, lipid rafts, and cell signaling pathways in neuroscience and biochemistry research.
• Cosmeceutical Formulations: Incorporated into premium skincare products for its potential membrane-stabilizing and anti-aging properties.
• Biochemical Reagent: Used as a substrate or intermediate in enzymatic studies involving phospholipases and lipid metabolism.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in chromatographic analysis of complex lipid mixtures.

Basic Information

Product Name	1-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	162440-05-3
Molecular Formula	C32H58NO8P
Molecular Weight	615.78 g/mol
Synonyms	DHA-PC; 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-phosphocholine; 1-DHA-2-lyso-PC; PC(22:6/0:0); LysoPC(22:6); 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-2-hydroxy-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine 1-docosahexaenoate
EINECS	Contact for details

Quality Control

Our 1-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and formulation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance in GMP-related applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep the material under the inert atmosphere after opening.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%
Peroxide Value	≤ 5.0 mEq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.