Description

Piperazine, 2,6-Dimethyl-, (Hydrochloride) (1:2), (2S,6S)- (Or Piperazine, 2,6-Dimethyl-, (Dihydrochloride), (2S-Trans)- (9Ci)) CAS NO 162240-96-2 is a high-purity, stereochemically defined chiral piperazine derivative, primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for synthesizing complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries who require reliable, high-quality chiral synthons for advanced drug discovery and production.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, particularly for central nervous system (CNS) and cardiovascular APIs.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and optimizing new chemical entities in drug discovery programs.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials where stereochemistry is crucial.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	Piperazine, 2,6-Dimethyl-, (Hydrochloride) (1:2), (2S,6S)- (Or Piperazine, 2,6-Dimethyl-, (Dihydrochloride), (2S-Trans)- (9Ci))
CAS No.	162240-96-2
Molecular Formula	C6H14N2 · 2HCl
Molecular Weight	215.11 g/mol
Synonyms	(2S,6S)-2,6-Dimethylpiperazine Dihydrochloride; (2S,trans)-2,6-Dimethylpiperazine Dihydrochloride; 2,6-Dimethylpiperazine Dihydrochloride (2S,6S)-isomer; cis-2,6-Dimethylpiperazine Dihydrochloride (S,S)-enantiomer; (S,S)-2,6-Dimethylpiperazine Dihydrochloride; L-2,6-Dimethylpiperazine Dihydrochloride; (2S,6S)-DMPP · 2HCl
EINECS	Contact for details

Quality Control

Our Piperazine, 2,6-Dimethyl-, (Hydrochloride) (1:2), (2S,6S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.