Description

Piperazine, 3,5-Dimethyl-1-(Phenylmethyl)-, (3S-Trans)- (9Ci) is a chiral, substituted piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and high-value building block for the development of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and chemical manufacturers engaged in the design and synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the creation of advanced, high-performance crop protection chemicals and pesticides.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	Piperazine, 3,5-Dimethyl-1-(Phenylmethyl)-, (3S-Trans)- (9Ci)
CAS No.	162240-95-1
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	(3S-trans)-3,5-Dimethyl-1-(phenylmethyl)piperazine; 1-Benzyl-(3S,5S)-3,5-dimethylpiperazine; (3S,5S)-1-Benzyl-3,5-dimethylpiperazine; trans-1-Benzyl-3,5-dimethylpiperazine; 1-Benzyl-cis-3,5-dimethylpiperazine (stereoisomer); Bz-3,5-DMP; Chiral 1-Benzyl-3,5-dimethylpiperazine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and chiral integrity, with specifications tailored to customer requirements. A comprehensive Certificate of Analysis (COA) detailing chiral purity (enantiomeric excess), chemical purity (by HPLC/GC), and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area Percent)
Chiral Purity (Chiral HPLC)	≥98.0% e.e. (Enantiomeric Excess)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.