Description

4-[(4-Chlorophenyl)-2-Pyridylmethoxy]Piperidine p-Nitrobenzoic Acid Salt is a high-purity, non-racemic salt form of a key piperidine-based intermediate. This compound is critical for ensuring consistent reactivity and purity in advanced pharmaceutical synthesis, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and methodologies.
• Process Chemistry: Employed in process optimization and scale-up studies for the commercial manufacturing of specialty chemicals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	4-[(4-Chlorophenyl)-2-Pyridylmethoxy]Piperidine p-Nitrobenzoic Acid Salt
CAS No.	161558-45-8
Molecular Formula	C24H22ClN2O5
Molecular Weight	453.90 g/mol
Synonyms	4-[(4-Chlorophenyl)(pyridin-2-yl)methoxy]piperidine 4-nitrobenzoate; 4-[(4-Chlorophenyl)-2-pyridylmethoxy]piperidine 4-nitrobenzoic acid salt; 4-Nitrobenzoic acid - 4-[(4-chlorophenyl)-2-pyridylmethoxy]piperidine (1:1); (R/S)-4-[(4-Chlorophenyl)(2-pyridinyl)methoxy]-1-piperidinecarboxylic acid 4-nitrophenyl ester salt; Piperidine, 4-[(4-chlorophenyl)-2-pyridinylmethoxy]-, 4-nitrobenzoate (1:1)
EINECS	Contact for details

Quality Control

Our 4-[(4-Chlorophenyl)-2-Pyridylmethoxy]Piperidine p-Nitrobenzoic Acid Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.