Description

1-(Methanesulfonyl)-Piperazine / 1-(Methanesulfonyl)-Piperazine Monohydrochloride is a high-purity, functionalized piperazine derivative primarily used as a key synthetic intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring a reliable building block with a reactive sulfonyl group for constructing complex molecular architectures. It is essential for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals, where precise chemical functionality and consistent quality are paramount.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides that require a piperazine-sulfonamide core structure.
• Organic Synthesis Reagent: Serves as a versatile reactant for introducing the methanesulfonyl-piperazine moiety into larger, more complex molecules in research and process chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions and developing novel synthetic methodologies.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands for catalysts and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(Methanesulfonyl)-Piperazine / 1-(Methanesulfonyl)-Piperazine Monohydrochloride
CAS No.	161357-89-7
Molecular Formula	C5H12N2O2S • HCl
Molecular Weight	200.69 g/mol (Free base: 164.22 g/mol)
Synonyms	1-(Methylsulfonyl)piperazine hydrochloride; N-(Methylsulfonyl)piperazine hydrochloride; Piperazine, 1-(methylsulfonyl)-, hydrochloride; Methanesulfonamide, N-(1-piperazinyl)-, hydrochloride; 1-Methanesulfonyl-piperazine HCl; 1-Piperazinylmethanesulfone hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Methanesulfonyl)-Piperazine Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.