Description

Bis(2-Cyanoethyl)-1-(n-tert-Butyloxycarbonyl)-D-Erythro-D-Sphingosine-1-Phosphate is a key, protected intermediate in the synthesis of complex bioactive sphingolipids. This compound is specifically designed for advanced pharmaceutical research and development, offering a critical building block for creating novel therapeutics. It is essential for scientists and manufacturers in the fields of oncology, immunology, and metabolic disease research who require high-purity, structurally defined sphingolipid analogs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of sphingosine-1-phosphate (S1P) receptor modulators and analogs.
• Drug Discovery Research: Used in medicinal chemistry programs to develop new chemical entities targeting S1P signaling pathways.
• Biochemical Probe Synthesis: Enables the creation of labeled or modified sphingolipids for studying cellular signaling mechanisms.
• Reference Standard Production: Serves as a high-purity standard for analytical method development and quality control of related active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies on lipid biology and sphingolipid metabolism.

Basic Information

Product Name	Bis(2-Cyanoethyl)-1-(n-tert-Butyloxycarbonyl)-D-Erythro-D-Sphingosine-1-Phosphate
CAS No.	161090-79-5
Molecular Formula	C₃₅H₅₅N₂O₈P
Molecular Weight	662.80 g/mol
Synonyms	Bis(2-cyanoethyl) (2S,3R,4E)-1-[(tert-Butoxycarbonyl)amino]-3-hydroxy-2-octadecene-4-yl phosphate; (2S,3R,4E)-1-(tert-Butoxycarbonylamino)-3-hydroxy-2-octadecene-4-yl bis(2-cyanoethyl) phosphate; BOC-Sphingosine-1-Phosphate Bis(2-cyanoethyl) Ester; D-erythro-Sphingosine-1-phosphate, N-BOC-protected, bis(2-cyanoethyl) ester; S1P Precursor (BOC, bis-cyanoethyl protected); N-BOC-D-erythro-Sphingosine-1-Phosphate Bis-Cyanoethyl Ester; Protected Sphingolipid Intermediate CAS 161090-79-5
EINECS	Contact for details

Quality Control

Our Bis(2-Cyanoethyl)-1-(n-tert-Butyloxycarbonyl)-D-Erythro-D-Sphingosine-1-Phosphate is manufactured under strict quality systems to ensure batch-to-batch consistency for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to high standards suitable for pharmaceutical intermediate applications, with specifications typically meeting or exceeding 95% purity (HPLC). Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in chloroform, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.