Description

5-Acetyl-2-Chloropyrazine is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive acetyl and chloro substituents, which enable precise molecular modifications and the construction of complex chemical architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging the pyrazine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Flavor and Fragrance Chemistry: Acts as a building block for synthesizing complex aroma compounds, given the pyrazine ring's role in nutty and roasted flavor profiles.
• Academic and R&D Laboratories: A fundamental reagent for methodological studies in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	5-Acetyl-2-Chloropyrazine
CAS No.	160252-31-3
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	2-Chloro-5-acetylpyrazine; 1-(2-Chloropyrazin-5-yl)ethanone; 2-Chloro-5-pyrazinyl methyl ketone; 5-Acetyl-2-chloropyrazine; 2-Chloro-5-acetylpyrazine; Ethanone, 1-(2-chloro-5-pyrazinyl)-
EINECS	Contact for details

Quality Control

Our 5-Acetyl-2-Chloropyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.