Description

4-Isopropylamino-Piperidine-1-Carboxylic Acid Benzyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and contract research organizations (CROs) engaged in novel drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing piperidine-based scaffolds and introducing the isopropylamino functional group.
• Research & Development (R&D): Essential for academic and industrial research in pharmacology and organic chemistry for developing new chemical entities.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of target APIs.
• Custom Synthesis: Serves as a starting material for contract manufacturing organizations (CMOs) producing specialized fine chemicals for clients.

Basic Information

Product Name	4-Isopropylamino-Piperidine-1-Carboxylic Acid Benzyl Ester
CAS No.	159874-34-7
Molecular Formula	C16H24N2O2
Molecular Weight	276.38 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-(isopropylamino)piperidine; 4-(Isopropylamino)-1-piperidinecarboxylic Acid Phenylmethyl Ester; 4-(Isopropylamino)piperidine-1-carboxylic Acid Benzyl Ester; Benzyl 4-(isopropylamino)piperidine-1-carboxylate; 1-CBZ-4-Isopropylaminopiperidine; N-Isopropyl-4-piperidinamine-1-carboxylic Acid Benzyl Ester
EINECS	Contact for details

Quality Control

Our 4-Isopropylamino-Piperidine-1-Carboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.