Description

1-Cbz-4-(Boc-Amino)Piperidine is a high-purity, dual-protected piperidine derivative of significant importance in advanced organic synthesis. This compound serves as a critical, multifunctional building block for constructing complex molecular architectures, offering orthogonal deprotection strategies. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology sectors for the synthesis of novel active ingredients and sophisticated intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Peptidomimetic Chemistry: Used to introduce constrained piperidine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Library Synthesis: Employed in combinatorial and parallel synthesis for generating diverse compound libraries for high-throughput screening (HTS).
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	1-Cbz-4-(Boc-Amino)Piperidine
CAS No.	159874-20-1
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-[(tert-butoxycarbonyl)amino]piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-(phenylmethoxycarbonyl)piperidine; 1-Carbobenzyloxy-4-(N-Boc-amino)piperidine; N-Boc-4-amino-1-Cbz-piperidine; 1-Cbz-4-N-Boc-piperidine; Piperidine, 1-[(phenylmethoxy)carbonyl]-4-[[(1,1-dimethylethoxy)carbonyl]amino]-; 4-(Boc-amino)-1-Cbz-piperidine
EINECS	Contact for details

Quality Control

Our 1-Cbz-4-(Boc-Amino)Piperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance with your research or cGMP guidelines, as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.