Description

tert-Butyl 4-(Cyanoacetyl)Piperazine-1-Carboxylate is a high-purity, versatile piperazine derivative and a key protected intermediate in advanced organic synthesis. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need it for its reactive cyanoacetyl and protected amine functionalities, which enable efficient multi-step synthetic routes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those containing piperazine and heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics & Bioactive Molecules: Employed in the construction of peptide analogs and other biologically active compounds where the piperazine moiety is a key pharmacophore.
• Material Science Precursor: Potential use as a monomer or functionalization agent in the synthesis of specialized polymers and advanced materials.

Basic Information

Product Name	tert-Butyl 4-(Cyanoacetyl)Piperazine-1-Carboxylate
CAS No.	159873-21-9
Molecular Formula	C12H19N3O3
Molecular Weight	253.30 g/mol
Synonyms	1-Boc-4-(cyanoacetyl)piperazine; 4-(Cyanoacetyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(2-cyanoacetyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(cyanoacetyl)piperazine; Boc-4-(cyanoacetyl)piperazine; N-Boc-4-(cyanoacetyl)piperazine; 4-(2-Cyanoacetyl)-N-Boc-piperazine; Piperazine, 4-(cyanoacetyl)-1-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Cyanoacetyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee consistency and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.