Description

Ethyl 2-Amino-2-(Pyrazin-2-Yl)Acetate Hcl is a high-purity, non-natural amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a functionalized pyrazine core with a protected amino acid ester moiety, enabling the construction of complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the pyrazine ring contributes to biological activity.
• Peptidomimetics Research: Serves as a constrained amino acid analog for creating novel peptide-like structures with enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the synthesis of specialized chelating ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized as a building block for creating labeled compounds and molecular probes to study biological pathways.
• Fine Chemical Production: Acts as a precursor for various specialty chemicals requiring a functionalized pyrazine scaffold.

Basic Information

Product Name	Ethyl 2-Amino-2-(Pyrazin-2-Yl)Acetate Hcl
CAS No.	159470-82-3
Molecular Formula	C8H12ClN3O2
Molecular Weight	217.65 g/mol
Synonyms	Ethyl 2-amino-2-(pyrazin-2-yl)acetate hydrochloride; 2-Pyrazineacetic acid, α-amino-, ethyl ester, hydrochloride; Ethyl α-amino-2-pyrazineacetate hydrochloride; (Amino-pyrazin-2-yl-acetic acid) ethyl ester hydrochloride; Ethyl 2-(pyrazin-2-yl)glycinate hydrochloride; 2-Amino-2-(2-pyrazinyl)acetic acid ethyl ester hydrochloride; Ethyl 2-(2-pyrazinyl)glycinate hydrochloride; Ethyl 2-pyrazin-2-yl-2-aminoacetate HCl
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-2-(Pyrazin-2-Yl)Acetate Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.