Description

2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine CAS NO 159407-32-6 is a highly purified, synthetic phospholipid featuring a docosahexaenoic acid (DHA) moiety, a critical ω-3 fatty acid. This compound is essential for advanced research and formulation in lipid-based delivery systems and cellular membrane studies. It is primarily utilized by pharmaceutical R&D teams, nutraceutical developers, and academic researchers focused on neuroscience, lipidomics, and targeted drug delivery.

Application

• Liposome and Nanoparticle Formulation: A key structural component for creating DHA-enriched liposomes and lipid nanoparticles (LNPs) for targeted drug and gene delivery.
• Biochemical and Cell Culture Research: Used to study membrane fluidity, lipid raft formation, and the role of DHA in neuronal and retinal cell function.
• Nutraceutical and Pharmaceutical Intermediates: Serves as a high-purity intermediate in the synthesis of specialized phospholipid-based supplements and active pharmaceutical ingredients (APIs).
• Model Membrane Systems: Incorporated into artificial membranes and vesicles to mimic specific biological membrane properties for biophysical studies.
• Reference Standard: Employed as an analytical standard in HPLC and mass spectrometry for the quantification of complex phospholipids in biological samples.

Basic Information

Product Name	2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	159407-32-6
Molecular Formula	C50H88NO8P
Molecular Weight	862.21 g/mol
Synonyms	22:6-18:0 PC; DHA-Sn-Glycero-3-Phosphocholine; 1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine; 18:0-22:6 PC; 1-Octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine; SDPC (DHA); Phosphatidylcholine, 1-stearoyl-2-docosahexaenoyl-; DHA-Phosphatidylcholine
EINECS	Contact for details

Quality Control

Our 2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality systems. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications for assay, related substances, and residual solvents, supporting its use in research and cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is hygroscopic (moisture-sensitive); allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR / NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.