Description

4-Bromomethypiperidine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its functional groups, which allow for selective deprotection and further functionalization, enabling the construction of complex nitrogen-containing heterocycles. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and psychiatric disorders.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides that require specific piperidine-based scaffolds.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for clients.

Basic Information

Item	Detail
Product Name	4-Bromomethypiperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	158407-04-6
Molecular Formula	C11H20BrNO2
Molecular Weight	278.19 g/mol
Synonyms	1-Boc-4-(bromomethyl)piperidine; tert-Butyl 4-(bromomethyl)piperidine-1-carboxylate; 4-(Bromomethyl)-1-(tert-butoxycarbonyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(bromomethyl)piperidine; N-Boc-4-(bromomethyl)piperidine; Boc-4-(bromomethyl)piperidine; 4-Bromomethyl-1-N-Boc-piperidine
EINECS	Contact for details

Quality Control

Our 4-Bromomethypiperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.