Description

Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Mercapto-, (7S-Trans)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound featuring a critical mercapto functional group. This advanced pharmaceutical intermediate is essential for the synthesis of complex molecules, particularly in the development of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) and other therapeutic areas.
• Drug Discovery Research: Used in medicinal chemistry for the design and construction of novel heterocyclic scaffolds with potential biological activity.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Chemical Biology Probes: The reactive mercapto group allows for conjugation, making it useful in creating probes for studying enzyme mechanisms or protein interactions.
• Asymmetric Synthesis: Utilized in stereoselective synthesis due to its defined (7S-Trans) configuration, enabling the production of enantiomerically pure compounds.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Mercapto-, (7S-Trans)- (9Ci)
CAS No.	158393-26-1
Molecular Formula	C7H12N2OS
Molecular Weight	172.25 g/mol
Synonyms	(7S-trans)-Hexahydro-7-mercaptopyrrolo[1,2-a]pyrazin-1(2H)-one; Hexahydro-7-mercapto-pyrrolo[1,2-a]pyrazin-1-one, (7S-trans)-; (7S-trans)-1,2,3,5,6,7-Hexahydro-7-mercaptopyrrolo[1,2-a]pyrazin-1-one; 7-Mercaptohexahydropyrrolo[1,2-a]pyrazin-1-one; (7S)-trans-Hexahydro-7-mercaptopyrrolo[1,2-a]pyrazin-1(2H)-one; Pyrrolo[1,2-a]pyrazine-1(2H)-one, hexahydro-7-mercapto-, (7S-trans)-
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Mercapto-, (7S-Trans)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.