Description

Pyrrolo[1,2-A]Pyrazin-1(2H)-One, 2-Ethylhexahydro-7-Hydroxy-, (7R-Cis)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. Its complex fused-ring structure with a defined chiral center makes it a valuable key intermediate or building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This product is primarily targeted at pharmaceutical R&D and specialty chemical manufacturers requiring precise molecular architecture for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Organic Synthesis Reagent: Used in advanced organic reactions to construct complex polycyclic frameworks found in natural products and bioactive molecules.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems due to its defined stereochemistry.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals where specific stereochemistry is required for functionality.
• Agrochemical Research: Potential intermediate for developing novel, high-specificity crop protection agents with complex molecular targets.

Basic Information

Item	Details
Product Name	Pyrrolo[1,2-A]Pyrazin-1(2H)-One, 2-Ethylhexahydro-7-Hydroxy-, (7R-Cis)- (9Ci)
CAS No.	158393-20-5
Molecular Formula	C10H16N2O2
Molecular Weight	196.25 g/mol
Synonyms	(7R-cis)-2-Ethylhexahydro-7-hydroxy-1H-pyrrolo[1,2-a]pyrazin-1-one; 1H-Pyrrolo[1,2-a]pyrazin-1-one, 2-ethylhexahydro-7-hydroxy-, (7R-cis)-; 2-Ethylhexahydro-7-hydroxy-1H-pyrrolo[1,2-a]pyrazin-1-one, (7R-cis)-; Pyrrolo[1,2-a]pyrazine-1-one derivative; Chiral pyrrolopyrazinone; Hexahydro-7-hydroxy-2-ethylpyrrolo[1,2-a]pyrazin-1(2H)-one, (7R-cis)-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and chiral purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if opened. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.