Description

Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Hydroxy-, (7R-Cis)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its complex fused-ring structure and chiral center, which are essential for constructing sophisticated molecular architectures with high biological relevance. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chiral Synthesis: Utilized in asymmetric synthesis to introduce the (7R-Cis) stereochemistry into target molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and high-value agrochemicals.
• Academic Research: Used in universities and R&D labs for methodological development in heterocyclic and natural product synthesis.
• Process Chemistry: Investigated for scale-up and optimization in the development of efficient commercial synthetic routes.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Hydroxy-, (7R-Cis)- (9Ci)
CAS No.	158393-18-1
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	(7R-cis)-Hexahydro-7-hydroxy-pyrrolo[1,2-a]pyrazin-1(2H)-one; Hexahydro-7-hydroxy-1H-pyrrolo[1,2-a]pyrazin-1-one, (7R-cis)-; (7R,8aS)-Octahydro-7-hydroxy-pyrrolo[1,2-a]pyrazin-1-one; 1H-Pyrrolo[1,2-a]pyrazin-1-one, hexahydro-7-hydroxy-, (7R-cis)-; 158393-18-1; (7R-cis)-Hexahydro-7-hydroxypyrrolo[1,2-a]pyrazin-1(2H)-one
EINECS	Contact for details

Quality Control

Our Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Hydroxy-, (7R-Cis)- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including chiral purity verification and impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.