Description

3-Chloro-2,4-Difluorobenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the benzoyl chloride group enables efficient amide or ester formation, and the specific halogen substitution pattern directs further selective chemical modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require precise intermediates for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing difluorophenyl motifs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides where the chloro-difluoro substitution offers unique biological activity.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated aromatic cores in electronic and display chemicals.
• Polymer Chemistry: Employed as a monomer or modifier to introduce halogenated aromatic units into high-performance polymers.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial R&D for constructing complex, fluorinated aromatic compounds.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	3-Chloro-2,4-Difluorobenzoyl Chloride
CAS No.	157373-00-7
Molecular Formula	C7H2Cl2F2O
Molecular Weight	210.99 g/mol
Synonyms	2,4-Difluoro-3-chlorobenzoyl chloride; 3-Chloro-2,4-difluorobenzoic acid chloride; Benzoyl chloride, 3-chloro-2,4-difluoro-; 157373-00-7; 3-Chloro-2,4-difluorobenzoic acid chloride; 3-Chloro-2,4-difluorobenzoylchloride; 3-Chloro-2,4-difluorobenzoyl Chloride (C7H2Cl2F2O)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4-Difluorobenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and all materials are supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to meet the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after initial opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.