Description

1H-Pyrazolo[3,4-B]Pyrazine-5-Carbonitrile,3,6-Diamino-(9Ci) is a high-purity heterocyclic organic compound with a fused pyrazolo-pyrazine core, serving as a critical advanced pharmaceutical intermediate. Its molecular structure, featuring amino and nitrile functional groups, makes it a versatile building block for the synthesis of complex, nitrogen-rich active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries, particularly for creating novel drug candidates and specialty chemicals. The CAS number for this compound is 157224-96-9.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its heterocyclic scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.
• Dye & Pigment Synthesis: Acts as an intermediate for creating specialized heterocyclic dyes and colorants.
• Academic & Contract Research: Supplied to universities and CROs for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyrazine-5-Carbonitrile,3,6-Diamino-(9Ci)
CAS No.	157224-96-9
Molecular Formula	C6H5N7
Molecular Weight	175.15 g/mol
Synonyms	3,6-Diamino-1H-pyrazolo[3,4-b]pyrazine-5-carbonitrile; 3,6-Diamino-5-cyanopyrazolo[3,4-b]pyrazine; 1H-Pyrazolo[3,4-b]pyrazine-5-carbonitrile, 3,6-diamino-; 157224-96-9; 3,6-Diamino-5-cyano-1H-pyrazolo[3,4-b]pyrazine; Pyrazolo[3,4-b]pyrazine-5-carbonitrile, 3,6-diamino-1H-; 5-Cyano-3,6-diamino-1H-pyrazolo[3,4-b]pyrazine
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyrazine-5-Carbonitrile,3,6-Diamino-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.