Description

Pyrazinecarboxylic Acid, 3-Amino-6-Cyano-5-Methoxy- (9Ci) is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring amino, cyano, and methoxy substituents on a pyrazine core, makes it a versatile precursor for constructing complex nitrogen-containing compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas like kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional organic materials, such as dyes, pigments, and electronic materials.
• Academic & Contract Research: Essential for chemical research in universities and CROs (Contract Research Organizations) exploring new heterocyclic chemistry.

Basic Information

Product Name	Pyrazinecarboxylic Acid, 3-Amino-6-Cyano-5-Methoxy- (9Ci)
CAS No.	157224-90-3
Molecular Formula	C8H6N4O3
Molecular Weight	206.16 g/mol
Synonyms	3-Amino-6-cyano-5-methoxypyrazine-2-carboxylic acid; 5-Methoxy-3-amino-6-cyanopyrazine-2-carboxylic acid; 2-Pyrazinecarboxylic acid, 3-amino-6-cyano-5-methoxy-; 3-Amino-5-methoxy-6-cyanopyrazine-2-carboxylic acid; 6-Cyano-5-methoxy-3-aminopyrazine-2-carboxylic acid; ACNP; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Pyrazinecarboxylic Acid, 3-Amino-6-Cyano-5-Methoxy- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (IR, NMR), and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.