Description

4-Imidazolidinecarboxylicacid,2-Oxo-,Methylester,(S)-(9Ci) is a chiral, non-proteinogenic amino acid derivative with a defined stereocenter. This compound is valued as a key synthetic intermediate and building block in advanced organic synthesis, particularly for constructing complex molecules with biological relevance. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and chiral catalysts.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and development of new therapeutic agents, including protease inhibitors and other enzyme-targeted drugs.
• Peptidomimetics & Bioactive Molecule Synthesis: Used as a constrained scaffold to mimic peptide secondary structures, aiding in the creation of more stable and potent bioactive compounds.
• Asymmetric Synthesis: Acts as a chiral auxiliary or precursor for ligands in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and constructing heterocyclic libraries.
• Agrochemical Intermediate: Potential use in the synthesis of advanced, chiral active ingredients for crop protection products.

Basic Information

Product Name	4-Imidazolidinecarboxylicacid,2-Oxo-,Methylester,(S)-(9Ci)
CAS No.	157001-86-0
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	(S)-Methyl 2-oxoimidazolidine-4-carboxylate; (4S)-2-Oxo-4-imidazolidinecarboxylic acid methyl ester; L-2-Oxoimidazolidine-4-carboxylic acid methyl ester; Methyl (S)-2-oxo-4-imidazolidinecarboxylate; (S)-4-Carbomethoxy-2-imidazolidinone; (S)-1,3-Diazinan-2-one-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. While typically supplied as a high-purity research grade, we can discuss custom synthesis under cGMP conditions for pharmaceutical development projects upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.