Description

Tisocalcitate CAS NO 156965-06-9 is a synthetic vitamin D analog with specific biological activity. This compound is critical for research and development in the pharmaceutical sector, particularly in the study of calcium metabolism and related endocrine pathways. It serves as a key intermediate or active ingredient for manufacturers developing treatments for conditions such as osteoporosis, secondary hyperparathyroidism, and other disorders of mineral homeostasis.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of advanced vitamin D-based therapeutics.
• Research & Development: Utilized in biochemical and pharmacological studies to investigate vitamin D receptor (VDR) activation and calcium-regulating mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Active Pharmaceutical Ingredient (API): Potential formulation into final dosage forms for clinical applications targeting bone and mineral disorders.
• Metabolic Pathway Studies: Used in academic and industrial research to elucidate the metabolic fate and biological effects of vitamin D analogs.

Basic Information

Product Name	Tisocalcitate
CAS No.	156965-06-9
Molecular Formula	C29H44O3
Molecular Weight	440.66 g/mol
Synonyms	1α,25-Dihydroxy-22-oxavitamin D3; 22-Oxacalcitriol; OCT; 1α,25-Dihydroxy-22-oxavitamin D3; 22-Oxa-1α,25-dihydroxyvitamin D3; 22-Oxa-1,25-dihydroxycholecalciferol; 22-Oxacalcitriol (OCT); Falecalcitriol intermediate
EINECS	Contact for details

Quality Control

Our Tisocalcitate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.