Description

Sanfetrinem is a synthetic trinem antibiotic belonging to the β-lactam class, specifically designed to combat a broad spectrum of Gram-positive and Gram-negative bacteria. Its advanced chemical structure offers enhanced stability against β-lactamase enzymes, making it a valuable candidate for research into overcoming antibiotic resistance. This compound is primarily utilized by pharmaceutical R&D teams and academic researchers focused on developing novel antibacterial agents and studying microbial resistance mechanisms.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of new-generation β-lactam antibiotics.
• Antimicrobial Resistance Studies: Used in microbiological research to investigate mechanisms of bacterial resistance and the efficacy of β-lactamase inhibitors.
• Preclinical Studies: Employed in in-vitro and in-vivo studies to evaluate pharmacokinetics, pharmacodynamics, and toxicity profiles of new antibacterial compounds.
• Chemical Synthesis: Acts as a sophisticated building block for the synthesis of novel trinem derivatives and related β-lactam structures.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in antibiotic analysis.

Basic Information

Product Name	Sanfetrinem
CAS No.	156769-21-0
Molecular Formula	C16H18N4O6S
Molecular Weight	394.40 g/mol
Synonyms	Sanfetrinem; GV 104326; GV-104326; (4R,5R,6S)-3-[[(3S,5S)-5-[(Aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Trinem antibiotic GV104326
EINECS	Contact for details

Quality Control

Our Sanfetrinem is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and NMR. A Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.