Description

Dexketoprofen Trometamol is the tromethamine salt of the active enantiomer of ketoprofen, a non-steroidal anti-inflammatory drug (NSAID). This high-purity active pharmaceutical ingredient (API) is valued for its potent analgesic and anti-inflammatory properties with a favorable pharmacokinetic profile. It is primarily required by pharmaceutical manufacturers for the formulation of prescription and over-the-counter medications targeting acute pain, inflammation, and fever.

Application

• Pharmaceutical API: Core ingredient in solid oral dosage forms such as tablets, capsules, and sachets for pain relief.
• Analgesic Formulations: Used in medications specifically designed for the management of acute mild to moderate pain, including dental pain and post-operative pain.
• Anti-inflammatory Medications: Key component in drugs formulated to reduce inflammation associated with conditions like osteoarthritis and musculoskeletal disorders.
• Antipyretic Drugs: Incorporated into formulations aimed at reducing fever.
• Generic Drug Manufacturing: Sourced by generic pharmaceutical companies for bioequivalent drug products.
• Clinical Research: Serves as a reference standard or raw material in pharmaceutical R&D and bioequivalence studies.

Basic Information

Product Name	Dexketoprofen Trometamol
CAS No.	156604-79-4
Molecular Formula	C19H24NO5
Molecular Weight	346.40 g/mol
Synonyms	Dexketoprofen Tromethamine; (S)-(+)-Ketoprofen Trometamol; Dexketoprofen Trometamol Salt; (+)-2-(3-Benzoylphenyl)propionic acid Tromethamine salt; Dexketoprofen Trometamol; Dexketoprofen Tromethamine Salt; AR-DF-121; Dexketoprofen Trometamol (USAN)
EINECS	Contact for details

Quality Control

Our Dexketoprofen Trometamol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including identification, assay, and control of specified impurities. Certificates of Analysis (COA) documenting compliance with in-house specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	+55.0° to +60.0°
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.